Aluminum Hydroxide and Magnesium Hydroxide

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	Pronunciation
	U.S. Brand Names
	Synonyms
	Generic Available
	Canadian Brand Names
	Use
	Pregnancy Risk Factor
	Adverse Reactions
	Drug Interactions
	Dosage

	Dietary Considerations
	Patient Education
	Nursing Implications
	Dental Health: Effects on Dental Treatment
	Dental Health: Vasoconstrictor/Local Anesthetic Precautions
	Mental Health: Effects on Mental Status
	Mental Health: Effects on Psychiatric Treatment
	Dosage Forms
	International Brand Names

Pronunciation

(a LOO mi num hye DROKS ide & mag NEE zhum hye DROK side)

U.S. Brand Names

Alamag [OTC]; Maalox® TC (Therapeutic Concentrate) [OTC] [DSC]; Rulox; Rulox No. 1

Synonyms

Magnesium Hydroxide and Aluminum Hydroxide

Generic Available

Canadian Brand Names

Diovol®; Diovol® Ex; Gelusil®; Gelusil® Extra Strength; Mylanta™; Univol®

Use

Antacid, hyperphosphatemia in renal failure

Pregnancy Risk Factor

C

Adverse Reactions

>10%: Gastrointestinal: Constipation, chalky taste, stomach cramps, fecal impaction

1% to 10%: Gastrointestinal: Nausea, vomiting, discoloration of feces (white speckles)

<1%: Hypophosphatemia, hypomagnesemia

Drug Interactions

Decreased effect: Tetracyclines, digoxin, indomethacin, or iron salts, isoniazid, allopurinol, benzodiazepines, corticosteroids, penicillamine, phenothiazines, ranitidine, ketoconazole, itraconazole

Dosage

Oral: 5-10 mL 4-6 times/day, between meals and at bedtime; may be used every hour for severe symptoms

Dietary Considerations

Should be taken 1-3 hours after meals.

Patient Education

Notify prescriber if relief is not obtained or if signs of bleeding from GI tract occur.

Nursing Implications

Administer 1-2 hours apart from oral drugs; shake suspensions well

Observe for constipation, fecal impaction, diarrhea, and hypophosphatemia

Dental Health: Effects on Dental Treatment

Key adverse event(s) related to dental treatment: Chalky taste. Aluminum and magnesium ions prevent GI absorption of tetracycline by forming a large ionized chelated molecule with the tetracyclines in the stomach. Aluminum hydroxide prevents GI absorption of ketoconazole and itraconazole by increasing the pH in the GI tract. Any of these drugs should be administered at least 1 hour before aluminum hydroxide.

Dental Health: Vasoconstrictor/Local Anesthetic Precautions

No information available to require special precautions

Mental Health: Effects on Mental Status

Mental Health: Effects on Psychiatric Treatment

Dosage Forms

[DSC] = Discontinued product

Suspension: Aluminum hydroxide 225 mg and magnesium hydroxide 200 mg per 5 mL (360 mL)

Alamag, Rulox: Aluminum hydroxide 225 mg and magnesium hydroxide 200 mg per 5 mL (360 mL)

Suspension, high potency (Maalox® TC) [DSC]: Aluminum hydroxide 600 mg and magnesium hydroxide 300 mg per 5 mL (360 mL)

Tablet, chewable:

Alamag: Aluminum hydroxide 300 mg and magnesium hydroxide 150 mg

Rulox No. 1: Aluminum hydroxide 200 mg and magnesium hydroxide 200 mg

International Brand Names

Diovol® (CA); Diovol® Ex (CA); Gelusil® (CA); Gelusil® Extra Strength (CA); Mylanta™ (CA); Univol® (CA)

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