EstroFactors® | Metagenics
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90 Tablets
Servings Per Container: 
Price: $62.75

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EstroFactors is a nutraceutical that captures some of the targeted ingredients in Estrium®— in tablet form—to promote healthy estrogen metabolism by addressing multiple aspects, including excretion.*


  • Designed to relieve common symptoms related to PMS, such as cramping, irritability, and breast tenderness*
  • May support breast health by promoting the hydroxylation and methylation of estrogen*
  • Features natural selective estrogen receptor modulators (SERMs) to lessen the impact of the more potent forms of estrogen*
  • Delivers calcium L-5-methyltetrahydrofolate, providing an advantage for those with genetic variations in folate metabolism*
Serving Size:

1 Tablet

Ingredient Amount Daily Value
Vitamin A (50% as Betatene® mixed carotenoids, 50% as retinyl palmitate) 833 IU  17% 
Vitamin D (as cholecalciferol) 66.7 IU  17% 
Vitamin E (as d-alpha tocopheryl succinate) 66.7 IU  222% 
Vitamin K (as phytonadione) 13 mcg  16% 
Vitamin B6 (as pyridoxine HCl) 16.7 mg  835% 
Folate (as calcium L-5-methyltetrahydrofolate) 266 mcg  67% 
Vitamin B12 (as methylcobalamin) 10 mcg  167% 
Isoflavones [from a proprietary blend of red clover (Trifolium pratense) aerial part extract and kudzu (Pueraria lobata) root extract] 33 mg 
Turmeric (Curcuma longa) Rhizome Extract [standardized to 95% (66.7 mg) curcuminoids] 70 mg 
Rosemary (Rosmarinus officinalis) Leaf Extract [standardized to 11% min phenolic diterpenes and 7.6% min sum of carnosol + carnosic acid] 66.7 mg 
Resveratrol (from Polygonum cuspidatum root extract) 0.67 mg 
Trimethylglycine (as betaine HCI) 66.7 mg 
Chrysin 30 mg 

Other Ingredients: Microcrystalline cellulose, stearic acid (vegetable), calcium silicate, croscarmellose sodium, silica, magnesium stearate (vegetable), and coating (hypromellose, medium chain triglycerides , and hydroxypropylcellulose).

Directions: Take one tablet daily with a meal or as directed by your healthcare practitioner.

This product is non-GMO and gluten free.

This product was not evaluated by Metagenics for use in women with known, or history of, hormone sensitive cancers.

Warning: Consult your healthcare practitioner before use if you are taking medications for birth control, or if you have a history of, or are being treated for cancer, liver disease or heart disease or if you develop symptoms of liver or kidney disease.

Storage: Keep tightly closed in a cool, dry place.

As Metafolin® U.S. Patent Nos. 5,997,915; 6,254,904.