How do I order Metagenics nutritional products?
Metagenics formulas are only available through licensed healthcare practitioners. Patients may find a practitioner.

How do I find a Metagenics practitioner near me?
Simply click here to locate a health care practitioner near you who offers Metagenics nutraceuticals and medical foods or to find a certified FirstLine Therapy practitioner who offers therapeutic lifestyle changes programs.

How do I contact Metagenics?
If you have questions about a specific Metagenics product or how to use it, please consult your health care practitioner. For other questions or comments, please Contact us Online.

What makes Metagenics different from most nutritional supplement companies?
A lot of things make us stand above other companies—a focus on patient health, quality manufacturing, ingredient testing, safety reviews, clinical testing, scientific research, unique formulas, and more. For specifics, check out the Quality Difference section.

What is a PRP complex?
PRP complex is a bovine colostrum-derived extract of proline-rich peptides consisting of less than 0.1% total colostrum. By virtue of a new, patented extraction technology, this naturally occurring protein from colostrum is showing exciting promise in protecting brain cells and promoting healthy brain aging.

What does "healthy brain aging" mean?
Many people equate getting older with memory loss and impaired cognition. Indeed, more than 24 million people worldwide have age-related cognitive impairment, and that number is increasing rapidly. Neuron impairment and oxidative stress naturally increase with age and are key factors contributing to memory loss and cognitive impairment. PRP complex promotes healthy brain aging by protecting the neuronal structure responsible for synthesizing acetylcholine and moderating oxidative stress, thereby aiding memory and cognition. Furthermore, in laboratory tests, PRP complex was shown to help maintain the stability of beta-amyloid, a substance whose breakdown appears to be associated with certain aspects of normal brain aging. The benefits of PRP complex for "healthy brain aging" have been confirmed in numerous clinical trials.

Who might benefit from PRP complex?
PRP complex may be beneficial for adults concerned with healthy brain aging. Since its mechanism of action does not affect acetylcholine (the neurotransmitter responsible for memory, speech, and reasoning), PRP complex may offer healthy, younger adults (younger than age 65) the opportunity to take action early to support healthy brain aging. PRP complex should not be used by children or women who are pregnant or nursing, as it has not been tested in these individuals. Anyone with suppressed immune function or taking immunomodulating agents should consult their health care practitioner before using PRP complex. Follow dosing instructions as outlined on the label.

Is PRP complex safe?
The source of PRP complex is bovine colostrum made by the mother’s body to boost her newborn’s immune and neurologic systems. PRP complex has been studied extensively over the last several decades. The safety and lack of toxicity of PRP complex is well documented and supported by both animal and human studies. However, those with dairy sensitivities should consult their practitioner prior to using PRP.

Is a person taking colostrum getting enough PRP complex?
No. The amounts of PRP complex in colostrum are minute. Using a new, patented technology, PRP complex is separated from whole colostrum, unveiling the full biological activity of these unique peptides. Also, the micellar structure of casein in colostrum may reduce the availability of the peptides, which are entrapped in casein and subsequently decrease the potency of its biological effects, making PRP complex more bioactive and bioavailable than plain colostrum.

How is PRP complex different than colostrum?
Unlike whole colostrum, PRP complex influences healthy brain function and is designed to exclude allergens commonly associated with milk products.

Can people with dairy sensitivities use PRP complex?
Yes, unless individuals are particularly sensitive. It is free of intact proteins (e.g., casein) associated with milk allergies, as well as lipids, minerals, and most carbohydrates (lactose). It is important to remember that food allergies and sensitivities can be complex. PRP complex may not be appropriate for individuals with severe milk allergies.

Why should someone take PRP complex when there are so many other brain foods and neuroprotective agents available?
PRP complex is unique, natural, and safe. It has been studied extensively and its safety and lack of toxicity are well-documented and supported by both animal and human studies. PRP complex has been shown to protect the neuronal structures responsible for making neurotransmitters, such as acetylcholine, which diminishes with age. Its powerful neuroprotective properties, in combination with its lack of neurotransmitter stimulating focus, make it suitable for adults wishing to use a natural product that does not influence neurotransmitters.

How does PRP complex compare with Ginkgo biloba for neuroprotection?
Gingko biloba, extracted from the leaves of the maiden hair tree, targets circulation. Ginkgo is primarily used to increase the blood supply to the brain by dilating blood vessels, reducing blood viscosity, modifying acetylcholine, and reducing the density of free radicals (oxidative stress). Ginkgo’s influence on acetylcholine positions this herb as beneficial for the older individual experiencing declining acetylcholine levels. Gingko’s inhibition of the platelet-activating factor may be an issue if used in conjunction with certain anti-platelet agents. In contrast, PRP complex does not directly influence acetylcholine. Rather, PRP complex protects the structures responsible for synthesis of acetylcholine and other neurotransmitters.

How does PRP complex compare with huperzine A for neuroprotection?
Huperzine A is a cognition-enhancing herb isolated from the Chinese Huperzia serrata. Huperzine A works as an acetylcholinesterase inhibitor, a compound that inhibits the breakdown of acetylcholine and cerebral antioxidants. However, over time, as the brain produces less and less acetylcholine, this mechanism of action becomes less effective. By comparison, PRP complex protects brain cells from oxidative damage without directly altering acetylcholine concentration.

How does PRP complex compare with vinpocetine for neuroprotection?
Vinpocetine is extracted from the leaves of the periwinkle (Vinca minor) plant. Like ginkgo extract, vinpocetine is a powerful botanical cognitive enhancer that helps to maintain healthy circulation in the brain, thus aiding in memory and the concentration of certain neurotransmitters involved in memory formation such as acetylcholine, dopamine, noradrenaline, and serotonin. By comparison, PRP complex protects the structures responsible for synthesis of acetylcholine and other neurotransmitters. It does not directly affect the levels of these neurotransmitters.

Can PRP complex be used safely with the above-mentioned herbs?
PRP complex may be utilized along with botanicals such as purified huperzine A, Ginkgo biloba extract, and vinpocetine when an individual is showing the early signs of age-related mild cognitive decline such as forgetfulness or minor lapses in memory.

How long should a person use PRP complex to get the health benefits?
Clinically beneficial effects have been delivered in as little as 100 mcg of PRP complex taken every other day for three weeks followed by a two-week break. This specific dosing regimen was established as effective in clinical research. No other natural agent has demonstrated these benefits at such a minimal amount, making PRP complex a safe, potent, and cost-effective neuroprotective agent.diovascular health.