Table of Contents > Herbs > Aloe
Aloe
Botanical Name:  Aloe vera/Aloe barbadensis/Aloe ferox 
Common Names:  Aloe Vera
 
Overview
Plant Description
What's It Made Of?
Available Forms
How to Take It
Precautions
Possible Interactions
Supporting Research

Overview

Aloe vera has a long history of use as a medicinal plant, with written records of its use going back to 1750 BC. Today it is grown in most subtropical and tropical locations, including the Caribbean, southern United States, Latin America, and the Middle East. Many people also grow a small potted version indoors for use in healing minor burns and cuts.

Aloe gel can be used to heal both internal and external wounds. It greatly speeds the healing of many skin injuries, including ulcerations, burns, hives and poison ivy. Aloe latex is a powerful laxative, but because it can cause painful cramping, it is not used frequently. Other gentler herbal laxatives such as cascara and senna are recommended first.

In smaller doses, aloe latex can help prevent kidney stones or reduce their size. It is also useful as a stool softener, particularly in people who have painful hemorrhoids.

Aloe juice is a liquid form of aloe gel that you can take internally. Because it has antibacterial properties, aloe juice can be used to treat bacterial infections in the gastro-intestinal tract. It is also effective for healing peptic ulcers because it reduces the stomach acids that aggravate ulcers. Aloe juice may also benefit persons with diabetes mellitus by reducing blood glucose levels.


Plant Description

Aloe vera is a perennial plant with yellow flowers. Its tough, fleshy, spearlike leaves can grow up to 20 inches long, and the whole plant up to 4 feet high. Only the leaves are used for medicine, but different parts of the leaves are used for different purposes. The clear, thick gel that is most commonly associated with aloe vera comes from the inner part of the leaf. Between this gel and the outer skin of the leaf are some special cells that contain a bitter yellow juice. When this juice is dried, it forms aloe latex.


What's It Made Of?

Aloe gel contains glycoproteins, protein-carbohydrate compounds that speed the healing process by stopping pain and inflammation, and polysaccharides, types of carbohydrates that stimulate skin growth and repair. The anthraquinones in aloe latex are chemical compounds that work as powerful laxatives, and in smaller amounts, they can help stop kidney stone formation.


Available Forms

Aloe gel is best fresh from an aloe plant, but it is also available commercially in a stabilized gel form. Aloe latex is available in a powdered form or in 500 mg capsules for use as a laxative. Aloe juice is a liquid form of the gel.


How to Take It

Pediatric

There is currently no information about the oral use of aloe for children. Pure aloe may be applied topically for minor skin irritations.

Adult

To use the gel topically, slit a leaf of an aloe plant lengthwise and remove the gel from inside. Apply liberally to the affected area.

For kidney stones and as a stool softener, take 0.05 to 0.2 g of dry aloe extract (latex) by mouth.


Precautions

Aloe gel is safe for external use, unless it causes a rare allergic reaction. Discontinue use if it irritates the skin. Aloe gel is not useful for treatment of deep wounds. Aloe latex may cause severe intestinal cramps or diarrhea. Pregnant or nursing women should not take aloe latex because it may cause uterine contractions and trigger miscarriage. Aloe latex is not recommended for gastrointestinal illness, intestinal obstruction, appendicitis, or stomach pain. It may aggravate ulcers, hemorrhoids, diverticulosis, diverticulitis, colitis, or irritable bowel syndrome. If taken over a long period of time, aloe latex can cause dependence or disturb the electrolyte balance. It may also cause urine to turn a harmless red color. Children under 12 should not use aloe latex.

Because aloe can decrease levels of potassium, aloe should not be used internally if you are taking digoxin; low potassium levels can increase the potential for toxic effects from this medication. Likewise, you should not use aloe if you are on diuretics because of the possibility of potassium loss from this combination.


Possible Interactions

The combination of aloe vera and glyburide, a medication used to treat Type II diabetes, may help control blood sugar and triglyceride levels in the blood. However, you should not use aloe vera in these instances without first consulting with your health care practitioner. Diabetic patients using aloe vera either alone or in combination with other antidiabetic medications need to be monitored closely by health care providers to avoid potential complications from low blood sugar levels.

Aloe vera may enhance the effects of hydrocortisone on swelling. Again, consult with your doctor before using aloe with hydrocortisone for conditions involving inflammation or swelling.


Supporting Research

Blitz JJ, et al. Aloe vera gel in peptic ulcer therapy: preliminary report. J Am Osteopath Assoc. 1963;62:731–735.

Blumenthal M, ed. The Complete German Commission E Monographs. Boston, Mass: Integrative Medicine Communications. 1998.

Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, Ore: Eclectic Medical; 1998:28-30.

Brinker F. The Toxicology of Botanical Medicines. Rev 2nd ed. Sandy, Ore: Eclectic Medical; 1996.

Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, et al. Antidiabetic activity of Aloe vera L. juice. II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomed. 1996;3:245-248.

Castleman M. The Healing Herbs. New York, NY: Bantam Books. 1991.

Chauhan O, Godhwani JL, Khanna NK, et al. Anti-inflammatory activity of Muktashukti bhasma. Indian J Exp Biol. 1998;36(10):985–989.

Danhof I. Potential benefits from orally-injested internal aloe vera gel. International Aloe Science Council Tenth Annual Aloe Scientific Semina; 1991; Irving, Texas.

Davis RH, Parker WL, Murdoch DP.Aloe vera as a biologically active vehicle for hydrocortisone acetate. J Am Podiatr Med Assoc. 1991;81:1-9.

De Smet PAGM, et al, eds. Adverse Effects of Herb Drugs 2. Berlin, Germany: Springer-Verlag; 1993.

Desai KN, Wei H, Lamartiniere CA. The preventive and therapeutic potential of the squalene-containing compound, Roidex, on tumor promotion and regression. Cancer Lett. 1996; 101(1):93-96.

Duke J. The Green Pharmacy. Emmaus, Penn: Rodale Press. 1997.

Fahim MS, Wang M. Zinc acetate and lyophilized Aloe barbadensis as vaginal contraceptive. Contraception. 1996;53:231–236.

Fulton JE Jr. The stimulation of postdermabrasion wound healing with stabilized aloe vera gel-polyethylene oxide dressing. J Dermatol Surg Onco. 1990;16:460.

Grindlay D, Reynolds T. The aloe vera phenomenon: a review of the properties and modern uses of the leaf parenchyma gel. J Ethnopharmacol. 1986;16:117–151.

Gruenwald J, Brendler T, Jaenicke C et al, eds. PDR for Herbal Medicines. Montvale, NJ: Medical Economics Company. 1998.

Heggers J, et al. Beneficial effects of aloe in wound healing. Phytother Res. 1993;7:S48–S52.

Murray M, Pizzorno J. Encyclopedia of Natural Medicine. Rocklin, Calif: Prima Publishing. 1991.

Murray M. Healing Power of Herbs. Rocklin, Calif: Prima Publishing. 1995.

Newall C, et al. Herbal Medicines. London, England: Pharmaceutical Press. 1996.

Paszkiewicz-Gadek A, Chlabicz J, Galasinski W. The influence of selected potential oncostatics of plant origin on the protein biosynthesis in vitro. Pol J Pharmacol. 1988;40(2):183–190.

Plemmons JM, et al. Evaluation of acemannan in the treatment of aphthous stomatitis. Wounds. 1994;6.

Ryndina AM, Lin'kov VI, Dadiomova MA, et al. Experience using antihypoxic drugs in the treatment of acute neurosensory hearing loss in children with meningitis [in Russian]. Vestn Otorinolaringol. 1989;3–4(2):14–17.

Saoo K, et al. Antiviral activity of aloe extracts against cytomegalovirus. Phytother Res. 1996;10:348–350.

Schmidt JM, Greenspoon JS. Aloe vera dermal wound gel is associated with a delay in wound healing. Ostet Gynecol. 1991;78(1).

Shida, T. et al. 1985. Effect of aloe extract on peripheral phagocytosis in adult bronchial asthma. Planta Med 51.

Schmidt JM, Greenspoon JS. Aloe vera dermal wound gel is associated with a delay in wound healing. Ostet Gynecol. 1991;78(1).

Syed TA, et al. Management of psoriasis with aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study. Trop Med Int Health. 1996;1:505–509.

Tyler V. The Honest Herbal. New York, NY: Pharmaceutical Products Press. 1993.

Vazquez B, et al. Anti-inflammatory activity of extracts from aloe vera gel. J Ethnopharmacol. 1996;55:69–75.

Wichtl M, ed. Herbal Drugs and Phytopharmaceuticals. 2nd ed. Boca Raton, Fla: CRC Press; 1994.


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  Uses of this Herb
Burns
Constipation
Diabetes Mellitus
Hemorrhoids
Kidney Stones
Peptic Ulcer
Wounds
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Summary
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