| Barberry |
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| Botanical Name: |
Berberis vulgaris |
| Common Names: |
Berberry |
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| Overview |
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Medicinal use of barberry goes as far back as ancient Egypt, where pharaohs
and queens took it with fennel seed to ward off the plague. Today, it is said to
ease the pain of arthritis and rheumatism, and the flare-ups of psoriasis. The
types of infections that barberry can help fight involve the throat, urinary
tract, gastrointestinal tract, and lungs, as well as yeast infections and
diarrhea. The bark of the root and stem are used for medicine. Both are yellow, and
Native Americans and Europeans used them for dyeing cloth. But the ingredients
in the bark are also what make barberry a useful medicine. The bark contains
alkaloids that are considered antibiotic by some people, and which cause,
according to herbalists, infection-fighting stimulation of your body's mucous
membranes. In order to understand what this means, if you place a drop of barberry on
your tongue, you will probably feel your mouth water. This is not because it
tastes good; it's actually somewhat bitter. But as your mouth waters, according
to herbalists, it is helping the body to fight infections. It does this by
stimulating parts of your body's immune system. If you have been taking antibiotics frequently because you get the same
infections over and over again, your health care provider may discuss herbal
alternatives to prescription drugs. There are many reasons for this. Barberry
may help you feel better and give you a break from other treatments. Also,
resistance to antibiotics is rising. In order to avoid this, many providers are
looking into other ways to treat illnesses. Another reason is that your body
changes in response to antibiotics, and these changes are not always good. The
normal bacteria that we all have inside us, which actually helps us to fight
against infection, can get wiped out with regular antibiotics. Your provider may
want to help you restore these "good" bacteria by letting you have a little time
off from antibiotics. Barberry may also be recommended to you as an ointment for arthritis or
psoriasis for similar reasons: medicines used regularly to treat these
conditions can upset your body's balance. Often, the side effects caused by
strong medications trigger reactions in the body that can seem like an entirely
new illness. Whatever the reason, once you and your health care provider have decided that
discontinuing medications will pose no risk to your health, barberry may be
recommended. It may also be recommended as a preventive method.
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| Plant Description |
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Barberry is a shrub that can grow to about nine feet and has gray, thorny
branches. Its leaves have spiny teeth. Between April and June, bright yellow
flowers bloom. These become dark red berries in the fall, which grow in drooping
bunches. You can use the ripe berries for jam, or in ways similar to
cranberries. Barberries are a little more sour and less bitter than cranberries.
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| What's It Made Of? |
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Barberry bark and root bark contain many types of chemicals called
isoquinoline alkaloids. Scientists and researchers have studied these
constituents for many years, and have found that they do indeed have antibiotic
actions. Some of them lower fevers, reduce swelling, lower blood pressure, and
help normalize heart rate and the contractions of the heart muscle.
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| Available Forms |
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Barberry comes as tea, powdered in capsules, in fluid extracts or tinctures,
and as a topical ointment. Extracts are standardized to 8 to 12% isoquinoline
alkaloid content. |

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| How to Take It |
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Pediatric Barberry is not recommended for use in children because of the possibility of
a lethal overdose. Adult You should never take barberry longer than five to seven days. If your
stomach is sensitive, three to five days is probably long enough. For sore
throats, bladder infections, diarrhea, bronchitis, or yeast infections, choose
from the following: - Tea: 2 to 4g steeped dried root three times daily
- Tincture (a 1:5 solution made from herb and alcohol, or herb, alcohol,
and water): 3 to 6 ml (1/2 to 1 1/2 tsp three times daily)
- Dry extracts: 250 to 500 mg three times daily
- For arthritis/psoriasis/skin disorders: 10% extract of barberry in
ointment, applied to the skin three times daily
It is important to remember that some infections can be very dangerous if
regular antibiotics are not taken for them. Never try to take an herb like
barberry in place of a prescription antibiotic. Make sure to follow your health
care provider's instructions. |

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| Precautions |
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Barberry is safe with appropriate use, but do not use it if you are pregnant.
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| Possible Interactions |
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No noteworthy interactions (positive or negative) between barberry and
conventional medications are known to have been reported in the literature to
date. |

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| Supporting Research |
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Amin AH, Subbaiah, TV, Abbasi KM. Berberine sulfate: antimicrobial activity,
bioassay, and mode of action. Can J Microbiol.
1969;15:1067–1076. Bergner P. Goldenseal and the common cold; goldenseal substitutes. Medical
Herbalism: A Journal for the Clinical Practitioner. Winter
1996–1997;8:1. Blumenthal M, ed. The Complete German Commission E Monographs. Boston,
Mass: Integrative Medicine Communications; 1998. Foster S, Duke JA. A Field Guide to Medicinal Plants: Eastern and Central
North America. Boston, Mass: Houghton Mifflin; 1990. Fukuda H, Watanabe K, Kudo Y. Some observations on the cardiovascular effects
of 9-substituted berberines. Chem Pharm Bull.
1970;18(7):1299–1304. Harborn, J, Baxter H. Phytochemical Dictionary: A Handbook of Bioactive
Compounds from Plants. Washington DC: Taylor & Francis; 1993. Ivanovska N, Philipov S. Study on the antiinflammatory action of Berberis
vulgaris root extract, alkaloid fractions, and pure alkaloids. Int J
Immunopharmacol. 1996;18:552–561. Kowalchik C,Hylton W, eds. Rodale's Illustrated Encyclopedia of Herbs.
Emmaus Pa: Rodale Press; 1998. Leung A, Foster S. Encyclopedia of Common Natural Ingredients Used in
Food, Drugs, and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons;
1996. McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal Products
Associations's Botanical Safety Handbook. Boca Raton, Fla: CRC Press;
1996. Muller K, et al. The antipsoriatic Mahonia aquifolium and its active
constituents; I. Pro- and antioxidant properties and inhibition of
5-lipoxygenase. Planta Med. 1994;60:421–424. Murray M. The Healing Power of Herbs: the Enlightened Person's Guide to
the Wonders of Medicinal Plants. Rocklin, Calif: Prima Publishing; 1995. Murray M, Pizzorno J. Encyclopedia of Natural Medicine. 2nd ed.
Rocklin, Calif: Prima Publishing; 1998:310. Shamsa F, et al. Antihistaminic and anticholinergic activity of barberry
fruit (Berberis vulgaris) in the guinea-pig ileum. J Ethnopharmacol.
1999;64:161–166. Sotnikova R, et al. Relaxant properties of some aporphine alkaloids from
Mahonia aquifolium. Methods Find Exp Clin Pharmacol.
1997;19:589–597. Sun D, Courtney HS, Beachey EH. Berberine sulfate blocks adherence of
Streptococcus pyogenes to epithelial cells, fibronectin, and hexadecane.
Antimicrob Agents Chemother. 1988;32:1370–1374. Ulrichova J, Walterova D, Preininger V. Inhibition of butyryl cholinesterase
activity by some isoquinoline alkaloids. Planta Med.
1983;48:174–177. |

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The publisher does not accept any responsibility for the accuracy of
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of any of the information contained herein, including any injury and/or damage
to any person or property as a matter of product liability, negligence, or
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guide to self-medication. The reader is advised to discuss the information
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regarding dosage, precautions, warnings, interactions, and contraindications
before administering any drug, herb, or supplement discussed
herein.
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