Table of Contents > Herbs > American Ginseng
American Ginseng
Botanical Name:  Panax quinquefolium
 
Overview
Plant Description
What's It Made Of?
Available Forms
How to Take It
Precautions
Possible Interactions
Supporting Research

Overview

Asians consider ginseng the king of all herbs. American ginseng is similar enough to Asian ginseng to chemically have the same effects. American ginseng root is light tan and looks a bit like a human body. Herbalists hundreds of years ago took this likeness to mean that ginseng could cure all human ills. It has been used as a cure-all by many different cultures.

Ginseng is difficult to grow. This difficulty made it a good export crop early on in American history, because it was plentiful in North America. In 1718, American ginseng brought five dollars a pound in Canton, China. In 1773, 55 tons of American ginseng were sold to the Chinese. In 1824, 380 tons were exported. Even Daniel Boone traded ginseng.

According to alternative medicine practitioners, American and Asian ginsengs are useful in the treatment of diabetes, fatigue, for alleviating stress, and during convalescence, and Siberian ginseng for stress, fatigue, and impaired kidney function. Confusion regarding which ginseng (American, Asian, or Siberian) to use for stress, fatigue, and convalescence stems from the suggestion that active components in one type are superior to those in another type. Such superiority has not been demonstrated. Early Russian studies indicated that Siberian ginseng's positive effects exceed those of Asian ginseng's. These results are supported by empirical reports, but have been challenged by investigators who question the validity of the studies and the quality of the Siberian ginseng preparation. At this time, all three ginsengs are regarded as adaptogens, all three have the same side effects, and despite qualitative differences, each is used for similar treatments. Cost, standardization, and the reputation of the manufacturer may be the deciding factors in determining which product to use.

Ginseng increases stamina and well-being. Athletes take ginseng to increase both endurance and strength. These actions make it sound like a stimulant, such as coffee, but stimulants often affect the action of important parts of the body, so irritability, heart palpitations, addiction, and anxiety are some of the side effects that may result from stimulant use. Ginseng, on the other hand, acts without any of these negative effects.

Your doctor may recommend ginseng if you have just had an illness. If you are elderly, ginseng may shorten the time that it takes you to bounce back from illness or surgery. It may also help you to focus your thoughts if you have difficulty concentrating, especially in cases of attention deficit/hyperactivity disorder. In fact, a recent report suggests that this herb may be helpful in enhancing memory, learning, and behavior in patients with Alzheimer's disease.

If you are someone who tends to get a lot of colds or sore throats you may find that taking ginseng reduces the frequency of these conditions. Ginseng is an adaptogen, which means that it helps the body fight the effects of just about any kind of stress, be it viral, bacterial, emotional, or physical. The effects of stress may be as simple as headaches or colds, but they can also be more serious, such as accelerated aging, memory loss, heart disease, cancer, and arthritis.


Plant Description

The plant has leaves that grow in a circle around a straight stem. Yellowish-green umbrella-shaped flowers grow in the center and produce red berries. Wrinkles around the neck of the root tell how old the plant is. This is important because ginseng is not ready for use until it has grown for four to six years.


What's It Made Of?

Ginseng products are made from ginseng root and the long, thin offshoots called root hairs. The main chemical ingredients of American ginseng are ginsenosides and polysaccharide glycans (quinquefolans A, B, and C).


Available Forms

White ginseng (dried, peeled) is available in water, water-and-alcohol, or alcohol liquid extracts, and in powders or capsules.


How to Take It

Pediatric

This herb is not recommended for use in children because of its stimulant properties.

Adult

The recommended dose is 1 to 2 g fresh root, 0.6 to 2 g dried root, or 200 to 600 mg liquid extract daily.

If you are healthy and are using ginseng to increase your physical or mental performance, to prevent illness, or to improve resistance to stress, you should take ginseng at the recommended dosage in cycles. For example, take 1 to 2 g fresh root, 0.6 to 2 g dried root, or 200 to 600 mg liquid extract daily for 15 to 20 days, followed by two weeks without taking ginseng.

For help recovering from an illness, the elderly should either take 0.5 g twice a day for three months and then stop or take 0.5 g twice a day for a month, followed by a two-month break. Repeat if desired.

When taking American ginseng, use only standardized products. Standardization is the only way of assuring quality in herbal products. Choose white American ginseng, standardized to 0.03 percent ginsenosides, designated as Rb1.


Precautions

The American Herbal Products Association (AHPA) rates American ginseng as a class 2d herb, which indicates that specific restrictions apply. In this case, hypertension (high blood pressure) is the specific restriction, so people with hypertension should not take ginseng products. Likewise, you should not use ginseng with caffeine or other medications that stimulate the central nervous system because this herb may increase the effects of these substances, possibly making you feel nervous or causing sweating, insomnia, or irregular heartbeat.

People with heart disease, diabetes, and low blood pressure should use caution when taking American ginseng. Do not take ginseng during any acute illness. Do not use ginseng if you are pregnant because its safety during pregnancy has not been determined.


Possible Interactions

There have been reports of a possible interaction between ginseng and the antidepressant medication, phenelzine, resulting in symptoms ranging from manic-like episodes to headache and tremulousness. Therefore, you should not use ginseng with phenelzine.

There have been reports that American ginseng may possibly decrease the effectiveness of the blood-thinning medication, warfarin. If you are currently on warfarin therapy, you should refrain from taking American ginseng.


Supporting Research

Bahrke M, Morgan P. Evaluation of the ergogenic properties of ginseng. Sports Medicine. 1994;18:229–248.

Blumenthal M, ed. The Complete German Commission E Monographs. Boston, Mass: Integrative Medicine Communications; 1998.

Blumenthal M, Riggins C. Popular Herbs in the U.S. Market: Therapeutic Monographs. Austin, Tex: The American Botanical Council; 1997.

Chen X, et al. The effects of Panax quinquefolium saponin (PQS) and its monomer ginsenoside on heart. Chung Kuo Chung Yao Tsa Chih. 1994;19:617–20, 640.

Cheng TO. Ginseng-warfarin interaction. ACC Curr J Rev. 2000;9(1):84.

Foster S. Herbal Renaissance: Growing, Using and Understanding Herbs in the Modern World. Salt Lake City, Utah: Gibbs-Smith; 1993.

Hu SY. A contribution to our knowledge of ginseng. Am J Chin Med. 1977;5(1):1–23.

Huang KC. The Pharmacology of Chinese Herbs. Boca Raton, Fla: CRC Press; 1993.

Janetsky K, Morreale A. Probable interaction between warfarin and ginseng. Am J Health-Syst Pharm. 1997;54:692-693.

Jones BD, Runikis AM. Interaction of ginseng with phenelzine [letter]. J Clin Psychopharmacol. 1987;7(3):201-202.

Kowalchik C, Hylton W, eds. Rodale's Illustrated Encyclopedia of Herbs. Emmaus, Pa: Rodale Press; 1998.

Kwan CY. Vascular effects of selected antihypertensive drugs derived from traditional medicinal herbs. Clin Exp Pharmacol Physiol. 1995;(suppl 1):S297–S299. Review.

Lewis R, Wake G, Court G, et al. Non-ginsenoside nicotinic activity in ginseng species. Phytother Res. 1999;13(1):59–64.

Li J, et al. Panax quinquefolium saponins protects low density lipoproteins from oxidation. Life Sci. 1999;64:53–62.

Mantle D, Pickering AT, Perry AK. Medicinal plant extracts for the treatment of dementia: a review of their pharmacology, efficacy, and tolerability. CNS Drugs. 2000;13:201-213.

Martinez B, Staba EJ. The physiological effects of Aralia, Panax, and Eleutherococcus on exercised rats. Jpn J Pharmacol. 1984;35(2):79–85.

McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, Fla: CRC Press; 1996.

Murphy LL, et al. Effect of American ginseng (Panax quinquefolium) on male copulatory behavior in the rat. Physiol Behav. 1998;64:445–450.

Murray M. The Healing Power of Herbs: the Enlightened Person's Guide to the Wonders of Medicinal Plants. Rocklin, Calif: Prima Publishing; 1995.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health Care Professionals. London, England: The Pharmaceutical Press; 1996.

Oshima Y. Isolation and hypoglycemic activity of quinquefolans A, B, and C, glycans of Panax quinquefolium roots. J Nat Prod. 1987;50:188–190.

Schultz V, Hansel R, Tyler V. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. New York, NY: Springer; 1998.

Thornton L. The ethics of wildcrafting. The Herb Quarterly. 1998:41–46.

Waki I. Effects of a hypoglycemic component of Ginseng radix on insulin biosynthesis in normal and diabetic animals. J Pharmacobiodyn. 1982;5:547–554.

Yuan CS, et al. Modulation of American ginseng on brainstem GABAergic effects in rats. J Ethnopharmacol. 1998;62:215–222.


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