Table of Contents > Herbs > Valerian
Valerian
Botanical Name:  Valeriana officinalis
 
Overview
Plant Description
What's It Made Of?
Available Forms
How to Take It
Precautions
Possible Interactions
Supporting Research

Overview

Valerian eases insomnia, stress-related anxiety, and nervous restlessness. It may also ease menstrual and stomach cramps, and some types of headache. Its main use, however, is to help people sleep.

Doctors, researchers, and herbalists recommend valerian for the treatment of sleep problems because it is both safe and gentle. Unlike sleeping aids you may have already tried, valerian will not cause you to feel tired when you wake up, and it has few, if any, side effects. It has also been help in the treatment of attention deficit/hyperactivity disorder.


Plant Description

Valerian products are made from the root of a tall, wispy plant, which is grown to decorate gardens but also grows wild in damp grasslands. Its umbrella-like heads top grooved, erect, and hollow stems. Its dark green leaves are pointed at the tip and hairy underneath. Small, sweet-smelling white, light purple, or pink flowers bloom in June. The root is light grayish brown and smells like dirty socks.


What's It Made Of?

The manufacture of medicinal valerian products begins with pressed fresh root or powdered freeze-dried root (frozen below 400°C). Valerian pressed-root juice added to alcohol or glycerite (sweet, nonalcohol liquid) bases become fluidextracts or tinctures; powdered root goes into capsules and tablets. While we don't know all the plant chemicals that cause valerian's activity, valerenic acid and bornyl in its plant essential oils have important roles.


Available Forms

Valerian fluid extracts and tinctures are sold in alcohol or alcohol-free (glycerite) bases. Powdered valerian capsules or tablets are also available, and you can also find valerian tea.

Valerian products are commonly added to formulas that contain other calming herbs, such as passionflower (Passiflora incarnata), hops (Humulus lupulus), lemon balm (Melissa officinalis), and, more recently, kava (Piper methysticum). If your provider has recommended valerian to you, it is most likely because he or she feels valerian is the most specific remedy for your condition.


How to Take It

Valerian products should be standardized to contain 0.8% valerenic or valeric acid; standardization helps to assure quality control in herbal products.

Pediatric

Adjust the recommended adult dose to account for the child's weight. Most herbal dosages for adults are calculated on the basis of a 150 lb (70 kg) adult. Therefore, if the child weighs 50 lb (20 to 25 kg), the appropriate dose of valerian for this child would be 1/3 of the adult dosage.

Adult

To reduce nervousness, anxiety, or headache or menstrual pain, you may use any of the following. Dosages repeated three times a day will also help you sleep better.

  • 2 to 3 g dried root in tea, up to several times daily
  • 1/4 to 1/2 tsp (1 to 3 mL) tincture up to several times daily
  • 1/4 tsp (1 to 2 mL) fluid extract (1:1)
  • 150 to 300 mg valerian extract, dried or liquid, standardized to contain 0.8% valerenic acid, 1% to 1.5% valtrate

For insomnia, take one of the dosages at least 30 to 45 minutes before bedtime. It may take two weeks before an effect is noticed. Continue to take valerian for two to four weeks longer after sleep pattern improves. A total of four to six weeks is usually the length of treatment advised by herbalists.

After six weeks, take a two-week break to see how you sleep without valerian. If you still have difficulty sleeping, start another four-to-six week course of treatment, or talk with your health care provider about other herbal medicines that may be helpful.


Precautions

The American Herbal Products Association (AHPA) gives valerian a class 1 safety rating, which indicates that it is a very safe herb with a wide dosage range. Even so, it is always wise to follow the recommended dosage exactly.

If you are pregnant, you should consult with your physician before taking any medication, including herbs.

Some people have a "paradoxical reaction" to valerian. This means that instead of feeling calm or sleepy, they suddenly feel nervous and anxious after they take valerian. If this happens to you, stop taking valerian, and tell your health care provider. This reaction is rare and not life-threatening.


Possible Interactions

While no noteworthy interactions (positive or negative) between valerian and conventional medications are known to have been reported in the literature to date, valerian is a sedative herb that may increase the effects of alcohol and medications for anxiety and insomnia. Therefore, use valerian with caution, if at all, if you are taking benzodiazepines (anti-anxiety medications), barbiturates (medications often prescribed for sleep disorders), or other sedative medications (such as antihistamines).


Supporting Research

Andreatini R, Leite J. Effect of valepotriates on the behavior of rats in the elevated plus-maze during diazepam withdrawal. Eur J Pharmacol. 1994;260:233–235.

Balderer G, Borbely AA. Effect of valerian on human sleep. Psychopharmacol. 1985;87:406–409.

Blumenthal M, ed. The Complete German Commission E Monographs. Boston, Mass: Integrative Medicine Communications; 1998.

Blumenthal M, Riggins C. Popular Herbs in the U.S. Market: Therapeutic Monographs. Austin, Tex: The American Botanical Council; 1997.

Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, Ore: Eclectic Medical; 1998:133-134.

Brown D. Herbal Prescriptions for Better Health. Rocklin, Calif: Prima Publishing; 1996.

DeSmet PAGM,ed. Adverse Effects of Herbal Drugs. New York, NY: Springer-Verlag; 1997:3.

Diefenbach K, et al. Valerian effects on microstructure of sleep in insomniacs. (2nd Congress of the European Assoc. for Clinical Pharmacology and Therapeutics, Berlin, Germany, Sept. 17-20.) Eur J Clin Pharmacol. 1997;52 (suppl):A169.

D'Arcy PF. Adverse reactions and interactions with herbal medicines. Part 2—Drug interactions. Adverse Drug React Toxicol Rev. 1993;12(3):147–162.

Hendriks H, Bos R, Woerdenbag HJ, et al. Central nervous depressant activity of valerenic acid in the mouse. Planta Med. 1985;1:28–31.

Hiller K-O, Zetler G. Neuropharmacological studies on ethanol extracts of Valeriana officinalis L.: behavioral and anticonvulsant properties. Phyto Ther. 1996;10:145–151.

Hobbs C. The Herbal Prescriber. Santa Cruz, Calif. Botanica Press; 1995.

Kowalchik C, Hylton W, eds. Rodale's Illustrated Encyclopedia of Herbs. Emmaus, Pa: Rodale Press; 1998:495–496.

Leathwood PD. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav. 1982;17:65–71.

Leung A, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. 2nd ed. New York, NY: John Wiley and Sons; 1996.

Leuschner J, Muller J, Rudmann M. Characterization of the central nervous depressant activity of a commercially available valerian root extract. Arzneim-Forsch. 1993;43:638–641.

Lindahl O, Lindwall L. Double-blind study of a valerian preparation. Pharmacol Biochem Behav. 1989;32:1065–1066.

Lindahl O, Lindwall L. Double–blind study of valopotriates by hairy root cultures of Valeriana officinalis var. sambucifolia. Planta Med. 1992;58:A614.

McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, Fla: CRC Press; 1997:120.

Mennini T, Bernasconi P. In vitro study on the interaction of extracts and pure compounds from Valeriana officianalis roots with GABA, benzodiazepine, and barbiturate receptors. Fitoterapia. 1993;64:291–300.

Murray, MT. The Healing Power of Herbs: The Enlightened Person's Guide to the Wonders of Medicinal Plants. Rocklin, Calif: Prima Publishing; 1995.

Newall CA, Phillipson JD. Interactions of Herbs with Other Medicines. Kings Centre for Pharmacognosy, the School of Pharmacy, University of London. The European Phytojournal. 1998; 1. Available at: http://www.ex.ac.uk/phytonet/phytojournal/ .

Petkov V. Plants with hypotensive, antiatheromatous and coronarodilating actions. Am J Chin Med. 1979;7:197–236.

Rasmussen P. A role for phytotherapy in the treatment of benzodiazepine and opiate drug withdrawal. Eur J Herb Med. 1997;3(1):11–21.

Samuelsson G. Drugs of Natural Origin: A Textbook of Pharmacognosy. Stockholm, Sweden: The Swedish Pharmaceutical Press; 1992.

Santos MS. Synaptosomal GABA release as influenced by valerian root extract—involvement of the GABA carrier. Arch Int Pharmacodyn Ther. 1994; 327:220–231.

Schultz V, Hansel R, Tyler V. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. New York, NY: Springer-Verlag; 1998.

Seifert T. Therapeutic effects of valerian in nervous disorders: a field study. Therapeutikon. 1988;2(94).

Schultz H, Stolz C, Muller J. The effect of valerian extract on sleep polygraph in poor sleepers: a pilot study. Pharmacopsychiatry. 1994;27:147–151.

Wagner et al. Comparative studies on the sedative action of valeriana extracts, valepotriates, and their degradation products. Planta Med. 1980;39:358–365.

White L, Mavor S. Kids, Herbs, Health. Loveland, Colo: Interweave Press; 1998:22, 42.


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