Enzymes

Many people experience digestive discomfort on a daily basis. A largely overlooked factor may be enzymes—biological catalysts that are essential to break down protein, fat, and carbohydrates and assimilate important nutrients from food.

Reduced enzyme production can make it harder to digest food and assimilate nutrients. Several factors may influence enzyme activity and digestion, including poor eating habits (e.g., inadequate chewing of food), dietary choices, age, and high cooking temperatures.

All of the products in the SpectraZyme family use non-GMO ingredients and are clinically shown to support healthy digestion.* To ensure the quality and efficacy of every formula, we test each batch of product for enzyme activity, using methodologies published from both the Food Chemical Codex (FCC) and United States Pharmacopeia (USP), a compendium of standards used internationally for establishing the quality and purity of ingredients.

A functional digestive system is key to maintaining overall wellness. Our comprehensive formulas are designed to support proper digestion of proteins (including gluten), peptides, carbohydrates, fats, cellulose, maltose, lactose, and sucrose—for thorough digestive support you can count on.*

Products

SpectraZyme® Complete

Broad Spectrum Digestive Support*

$29.75

SpectraZyme® Metagest® (formerly Metagest)

Stomach Acid Support* Features Betaine HCl & Pepsin

$25.00

SpectraZyme® Pan 9x ES

Bioactive Pancreatic Enzymes for Digestive Support*

$60.00

SpectraZyme® Pan 9x

Bioactive Pancreatic Enzymes for Digestive Support*

$42.25

SpectraZyme® Gluten Digest

Targeted Support for Enzymatic Breakdown of Gluten*

$41.50

Learn More

Enzymes Are Essential for Healthy Digestion

Up to 1 in 4 Americans suffer from digestive discomfort that affects daily living.1 A largely overlooked factor may be enzymes—biological catalysts that are essential to break down protein, fat, and carbohydrates and assimilate important nutrients from food.

How Enzyme Activity Works to Facilitate Digestion
Enzyme activity begins in the mouth where salivary amylase, lingual lipase, and ptyalin initiate starch and fat digestion. In the stomach, hydrochloric acid activates pepsinogen to pepsin, which breaks down protein, and gastric lipase begins the hydrolysis of fats. Most digestion and absorption takes place in the small intestine and is mediated by pancreatic amylase, protease, lipase, and bile salts.

Many Factors Affect Enzyme Production & Digestion
Reduced enzyme production can make it harder to digest food and assimilate nutrients. Several factors may influence enzyme activity and digestion:

Poor eating habits, such as inadequate chewing of food, “eating on the run,” or eating late in the day
Dietary choices such as refined carbohydrates, fat, and high amounts of meat
Hydrochloric acid and enzyme secretion generally decline with age
Naturally occurring enzymes are destroyed when food is cooked at 118° F or greater

The SpectraZyme Difference

SpectraZyme enzyme formulas, recommended by your healthcare practitioner, provide you exceptional quality and personalized options that feature a wide array of digestive enzymes:

Enzyme	What it Helps Break Down for Digestion
Amylase	Carbohydrates (starches and other polysaccharides)
Protease	Protein (large amino acid chains)
Peptides & Pepsin	Peptides (smaller amino acid chains)
Lipase	Fats (triglycerides and other lipids)
Lactase	Lactose (milk sugar)
Cellulase, Pectinase, Xylanase & Hemicellulase	Cellulose, pectin, xylan & hemicellulose (plant fibers and carbohydrates)
Maltase	PMaltose (malt sugar)
Invertase	Sucrose (table sugar)

Which SpectraZyme Formula is Right for You?

Product	Ideal for:
SpectraZyme Complete	Wild digestive support¹³, protein breakdown^{13, 14}, carbohydrate breakdown^{15, 16}, fat breakdown^{17, 18}, plant cellulose breakdown¹⁹, lactose breakdown²⁰, sucrose breakdown¹⁶, non-animal derived
SpectraZyme Gluten Digest	Significant gluten breakdown^{8, 10, 11}, non-animal derived
SpectraZyme Pan 9x	Wild digestive support¹³, protein breakdown^{13, 14}, carbohydrate breakdown^{15, 16}, fat breakdown^{17, 18}
SpectraZyme Pan 9x ES	Extra strength digestive support¹⁴, protein breakdown^{13, 14}, carbohydrate breakdown^{15, 16}, fat breakdown^{17, 18}
SpectraZyme Metagest	Protein breakdown, stomach acid support²¹

1. NPD Group. Percentage of U.S. adults trying to cut down or avoid gluten in their diets reaches new high in 2013. Available at www.npd.com/news/press-releases. Accessed March 17, 2015.
2. Wieser H. Food Microbiol. 2007;24:115-119.
3. Bethune MT, Khosla C. Methods Enzymol. 2012:502:241-271.
4. Caputo I, et al. Enzyme Res. 2010;2010:174354.
5. Hausch F, et al. Am J Physiol Gastrointest Liver Physiol. 2002;283:G996-G1003.
6. Edens L, et al. J Agric Food Chem. 2005;53:7950-7957.
7. Ehren J, et al. PLoS One. 2009;4(7):1-10.
8. Stepniak D, et al. Am J Physiol Gastrointest Liver Physiol. 2006;291:G621-G629.
9. Montserrat V, et al. Food Chem. 2015;174:440-445.
10. Mitea C, et al. Gut. 2008;57:25-32.
11. Salden B, et al. Gastroenterology. 2014;146(5):S-545 (abstract).
12. DSM research in collaboration with Leiden University Medical Center in The Netherlands. Manuscript submitted for publication.
13. Omogbenigun FO, Nyachoti CM, Slominski BA. J Anim Sci. 2004;82(4):1053-1061.
14. Bragelmann R, Armbrecht U, Rosemeyer D, Schneider B, Zilly W, Stockbrugger RW. Eur J Gastroenterol Hepatol. 1999;11(3):231-237.
15. Siivaramakrishnan S, Gangadharan D, Nampoothiri K, Soccol CR, Pandey A. J Sci Ind Res. 2007;66:621-626.
16. Jonsson KA, Bodemar G. Hepatogastroenterology. 1990;37:217-222.
17. Delhaye M, Meuris S, Gohimont AC, Buedts K, Cremer M. Eur J Gastroenterol Hepatol. 1996; 8:699-703.
18. Opekun AR, Sutton FM, Graham DY. Aliment Pharmacol Ther. 1997;11:981-986.
19. Thomson Healthcare. Available at: www.pdrhealth.com/drug_info/
nmdrugprofiles/nutsupdrugs/sup_0328.shtml. Accessed November 20, 2014.
20. Sanders SW, Tolman KG, Reitberg DP. Clin Pharm. 1992;11:533-538.
21. Dev Bardhan K, Strugala V, Dettmar PW. Int J Otolaryngol. 2012;2012:646901.