Omega-3 and Fish Oil Supplements
Pure, potent omega-3 and fish oil supplements to support your daily heart…
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OmegaGenics® 5-in-1 Fish Oil 1000 mg EPA-DHA
5-in-1 omega-3 fish oil supplement for heart, brain, eye, immune and joint health*
4.6Average Rating 4.6OmegaGenics® 3-in-1 Fish Oil 720 mg EPA-DHA
3-in-1 fish oil supplement for heart, eye, and joint health*
4.7Average Rating 4.7OmegaGenics® Fish Oil EPA 1200 mg
High-potency EPA omega-3 for heart health support*
4.9Average Rating 4.9
OmegaGenics® 5-in-1 Liquid Fish Oil 2400 mg EPA-DHA
Supports heart, brain, eye, immune and joint health*
4.8Average Rating 4.8OmegaGenics® Fish Oil Mega 10®
Supports immune function and cardiovascular health*
5.0Average Rating 5.0
OmegaGenics® Fish Oil EPA-DHA 500 mg
A purified omega-3 fish oil for daily heart health*
4.9Average Rating 4.9Omegagenics® Kids DHA
Chewable omega-3 support for healthy brain and eye function.*
5.0Average Rating 5.0
OmegaGenics® Fish Oil EPA-DHA 300 mg
Supports heart health*
5.0Average Rating 5.0
OmegaGenics® Fish Oil Neuro 1000 mg
Concentrated omega-3 fish oil for brain health and focus.*
4.0Average Rating 4.0
OmegaGenics® Algae Omega-3s 300 mg
Supports heart health*
5.0Average Rating 5.0OmegaGenics® Borage Seed GLA Oil 240 mg
Supports prostaglandin metabolism*
5.0Average Rating 5.0Daily Detox Support by Dr. Patricia Guevara-Channell, MD
The ultimate detox supplement stack curated by Dr. Patricia Guevara-Channell, MD
Price reduced to5.0Average Rating 5.0OmegaGenics® Evening Primrose Oil
Support for prostaglandin metabolism.*
Omega & Fish Oil Articles
- Omega-3s & Fish Oil
Omega-3 Fatty Acids Benefits Explained: Brain Health, Inflammation, and How Much You Really Need
Most people who start taking an omega-3 supplement make the same choice: they grab the most familiar bottle, take the dose on the label, and assume that is enough. They rarely check how much EPA and DHA they are actually getting, whether they are taking it at a time that supports absorption, or how long it will be before anything noticeable happens.
By Dr. Cassie Story - Omega-3s & Fish Oil
Omega-3 Dosage, Timing, and What to Expect: How Much Do You Need Per Day?
Omega-3 dosage isn't one-size-fits-all, and total fish oil isn't the number that matters. Keep reading to learn how much EPA and DHA to aim for, when to take it, and how long before you'll notice a difference.
By Dr. Cassie Story - Omega-3s & Fish Oil
Which Omega-3 Supplement Is Best for You? A Guide to Choosing the Right Formula
By Dr. Cassie Story - Essential Wellness
More Than a Number: The Difference Between Omega-3, -6, and -9
By Metagenics Medical Education Team
Benefits of Taking Omega-3 Supplements
Omega-3 fatty acids are essential. Your body can't make them, so what you eat (and supplement) matters. EPA and DHA, the two most researched forms, play a direct role in how your heart, brain, and joints function day to day.
Heart Health
EPA and DHA help maintain healthy triglyceride levels already within the normal range and support overall cardiovascular function. For anyone focused on long-term heart health, consistent omega-3 intake is one of the most studied lifestyle interventions available.
Brain and Cognitive Support
DHA makes up a significant portion of the brain's structural fat. Adequate intake is associated with normal cognitive function, mental clarity, and mood balance. Whether you're managing daily stress or thinking about long-term brain health, omega-3s are a foundational piece.
Joint Comfort and Mobility
EPA plays a role in supporting the body's natural response to exercise-related stress in the joints. Regular omega-3 supplementation is commonly recommended by healthcare practitioners for people who want to stay active and comfortable.
Choosing The Best Omega-3 Supplement
Not all fish oil supplements are equal. Potency, purity, form, and sourcing all affect whether the omega-3s in a capsule actually reach your cells and do their job.
EPA and DHA Concentration
Look at the actual milligrams of EPA and DHA per serving, not total fish oil. A 1,000 mg fish oil capsule may contain only 300 mg of active omega-3s. Higher concentration means fewer capsules and more predictable results.
Triglyceride vs. Ethyl Ester Form
Omega-3s in triglyceride (TG) form are more bioavailable than ethyl ester (EE) forms, meaning your body absorbs more of what's in each dose. Metagenics formulas are built around triglyceride-form EPA and DHA for this reason.
Purity and Third-Party Testing
Fish oil is only as good as its sourcing and manufacturing standards. Metagenics products are tested for heavy metals, PCBs, and oxidation levels that can affect both safety and efficacy. Look for products with verifiable purity standards, not just label claims.
Sustainable Sourcing
Metagenics sources omega-3s from sustainably managed fisheries. If environmental impact matters to your supplement decisions, sourcing transparency is a meaningful differentiator.
Omega-3 & Fish Oil Frequently Asked Questions
Omega-3 supplements are best taken with a meal that contains fat. Because EPA and DHA are fat-soluble, eating them alongside dietary fat improves absorption. Most people take them with lunch or dinner to avoid any mild digestive discomfort that can come with taking fish oil on an empty stomach. Consistency matters more than timing: pick a meal you eat every day and make it part of that routine.
For general health maintenance, most research points to 500-1,000 mg of combined EPA and DHA per day. For targeted support, cardiovascular health, joint comfort, or mood, practitioners often recommend 1,000-3,000 mg daily.¹,² Your ideal dose depends on your health goals, diet, and any guidance from your healthcare provider.
Metagenics products are formulated to make it easy to reach clinically relevant doses without taking multiple capsules.
Fish oil is the delivery vehicle. Omega-3s, specifically EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the active compounds inside it. Not all fish oil supplements contain the same amount of EPA and DHA, which is why total fish oil milligrams on a label can be misleading. When comparing products, focus on the EPA and DHA content per serving, not the fish oil total.
Yes. Omega-3s are generally well-tolerated alongside most supplements, including multivitamins, vitamin D, magnesium, and probiotics. If you're taking blood-thinning medications or high-dose supplements that affect clotting, speak with your healthcare provider before adding a high-dose omega-3 product.
As a standard practice, Metagenics recommends consulting a practitioner when building a supplement protocol, especially if managing an existing health condition.
References:
National Institutes of Health, Office of Dietary Supplements. Omega-3 Fatty Acids: Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/
Siscovick DS, Barringer TA, Fretts AM, et al. Omega-3 polyunsaturated fatty acid (fish oil) supplementation and the prevention of clinical cardiovascular disease. Circulation. 2017;135(15):e867-e884. doi:10.1161/CIR.0000000000000482
Global Organization for EPA and DHA Omega-3s (GOED). Intake recommendations and bioavailability data. https://goedomega3.com