Stay sharp, focused, and balanced with science-backed brain health supple…
5-in-1 omega-3 fish oil supplement for heart, brain, eye, immune and joint health*
Collagen + creatine powder for strength, energy, and cognitive support*
3-in-1 fish oil supplement for heart, eye, and joint health*
More strength. More muscle. Powered by creatine, betaine and taurine to fuel performance.*†
Supports vascular system by aiding the methylation process*
Support memory, focus, and mental clarity.* Clinically studied to improve modeled cognitive age by 7.5 years^
Supports heart and nervous system health.*
Stress leaving you feeling drained? Support resilience & stamina with Adreset® adaptogen supplements
Supports heart health and energy production.*
Serenagen is a classic herbal stress management formula used in traditional Chinese medicine to nourish and quiet the heart.*
Fuel energy & support heart muscle function with absorbable CoQ10*
Supports brain and nerve health*
Targeted nutritional support for brain health.*
Nutritional support for adrenal function.*
Supports calmness and relaxation.*
Supports memory and cognitive function*
Support for cortisol metabolism*
High-potency supplement for energy & heart health
Mitochondria & cell function support.*
Supports cardiometabolic health.*
Supports respiratory and immune health.*
Energy and stress tolerance support*
Chewable omega-3 support for healthy brain and eye function.*
Helps to increase ketone production†* featuring MCT oil concentrated to 90% C8 + C10
Magnesium L-threonate pairs magnesium with L-threonic acid, allowing it to cross the blood-brain barrier more effectively than standard forms. Magtein®, the patented, clinically studied form, has been linked to improved memory, attention, and cognitive performance in as little as six weeks. Learn how it works and what the research shows.
Most people who start taking an omega-3 supplement make the same choice: they grab the most familiar bottle, take the dose on the label, and assume that is enough. They rarely check how much EPA and DHA they are actually getting, whether they are taking it at a time that supports absorption, or how long it will be before anything noticeable happens.
Creatine and collagen work on different systems, which is exactly why they stack well: creatine regenerates ATP inside muscle cells to support strength, power, and cognitive function; collagen supplies amino acids that support joints, tendons, ligaments, and skin. Effective daily doses are 3–5 g creatine monohydrate and 2.5–15 g hydrolyzed collagen, or 40 mg UC-II for cartilage. Learn how to take them together.
Your brain is about 2% of your body weight, yet it uses roughly 20% of your body's energy. It runs everything from your heartbeat to your to-do list. Supporting it is not only about remembering where you left your keys. It is about how you sleep, how you handle stress, and how well you keep doing the things you love as the years go by.1
Brain health supplements work best alongside the habits that matter most: sleep, movement, good food, and staying social. Think of them as support staff, not the whole team.
Your brain is the control center for your whole body. The brainstem keeps your heart beating and your lungs breathing without you ever thinking about it. The hypothalamus, a small region deep in the brain, helps run your sleep-wake cycle and your body's response to stress.2
The connection runs both ways. Good sleep gives your brain time to clear out waste and store new memories, while poor sleep leaves you foggy the next day.3 Your brain and immune system also stay in constant contact, which is one reason long-term stress can wear down both.3,4
Mood, motivation, and calm all start in the brain. Chemical messengers called neurotransmitters, such as serotonin and dopamine, carry signals between brain cells and shape how you feel from moment to moment.
Stress is part of life, but when it sticks around it can disrupt sleep, digestion, and mood, and it can make it harder to focus. That is why brain health and emotional health are really the same conversation. Steady routines, regular exercise, and time with people you care about all help your brain handle pressure. Adaptogens like those in Adreset® can support stress resilience as part of that routine.*4
Cognitive health is your ability to think, learn, and remember clearly. It is what lets you manage your money, drive, cook, keep up with medications, and stay connected with friends. Some changes are a normal part of aging, like taking a little longer to recall a name. Many habits that support your heart and blood pressure also support your brain, so small choices today add up over time.5
Certain nutrients deserve extra attention with age. Many adults over 50 absorb less vitamin B12 from food, and low B12 can show up as poor memory and fatigue. Some common medications, including metformin and acid reducers, can lower B12 levels too.6
Vitamin B12 is the vitamin most closely tied to memory, because it helps keep nerve cells healthy and low levels can cause poor memory and confusion. Folate works alongside B12, and adults over 50, vegetarians, and people taking metformin or acid reducers are more likely to run low.⁶
Memory support also comes from nutrients that are not vitamins, like omega-3 DHA and magnesium L-threonate. In a six-week randomized trial in adults reporting poor sleep, magnesium L-threonate improved overall cognition scores compared with placebo, with the clearest effects on memory.*⁷ Explore Intrinsi Vitamin B12-Folate and Magtein® above.
Omega-3s, creatine, and magnesium L-threonate are three of the most researched supplements for brain function. DHA, an omega-3 fat, is found in high levels in the brain.⁸ Creatine helps supply energy to brain cells, and a review of randomized trials in healthy people found it may support short-term memory and reasoning.⁹ Magnesium L-threonate has one randomized trial behind it showing improvements in overall cognition and reaction time over six weeks.*⁷ Compare options in our brain health supplements lineup.
Good cognitive supplements support memory, focus, and clear thinking, and the right pick depends on your goal. For everyday memory, magnesium L-threonate and omega-3s are reasonable starting points.⁷,⁸ For brain energy, creatine is worth a look.⁹ If you want one simple routine, an all-in-one pack like Wellness Essentials® Brain Health combines several of these in one daily packet. Memory-specific formulas like Ceriva® are best used with a practitioner’s guidance. Find your fit in the lineup above.
The best supplements for focus and concentration pair well-studied nutrients with good sleep. In its randomized trial, magnesium L-threonate improved reaction time, a measure of mental processing speed, compared with placebo.*⁷ DHA from fish oil supports cognitive health.*⁸ Caffeine can sharpen focus for a few hours, but too much or too late in the day can hurt your sleep, which is the foundation of concentration.³ Start with Magtein® or OmegaGenics® 5-in-1 Fish Oil above.
1. Raichle ME, Gusnard DA. Appraising the brain's energy budget. Proc Natl Acad Sci U S A. 2002;99(16):10237-10239. doi:10.1073/pnas.172399499
2. National Institute of Neurological Disorders and Stroke. Brain basics: know your brain. Accessed October 8, 2026. https://www.ninds.nih.gov/health-information/public-education/brain-basics/brain-basics-know-your-brain
3. National Institute of Neurological Disorders and Stroke. Brain basics: understanding sleep. Accessed October 8, 2026. https://www.ninds.nih.gov/health-information/public-education/brain-basics/brain-basics-understanding-sleep
4. National Institute of Mental Health. I'm so stressed out! fact sheet. Accessed October 8, 2026. https://www.nimh.nih.gov/health/publications/so-stressed-out-fact-sheet
5. National Institute on Aging. Cognitive health and older adults. Accessed October 8, 2026. https://www.nia.nih.gov/health/brain-health/cognitive-health-and-older-adults
6. National Institutes of Health, Office of Dietary Supplements. Vitamin B12: fact sheet for consumers. Accessed October 8, 2026. https://ods.od.nih.gov/factsheets/VitaminB12-Consumer/
7. Lopresti AL, Smith SJ. The effects of magnesium L-threonate (Magtein) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial. Front Nutr. 2026;12:1729164. doi:10.3389/fnut.2025.1729164
8. National Institutes of Health, Office of Dietary Supplements. Omega-3 fatty acids: fact sheet for consumers. Accessed October 8, 2026. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/
9. Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: a systematic review of randomized controlled trials. Exp Gerontol. 2018;108:166-173.
