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Supplement stacks that make your wellness easier.

Built by practitioners, PracStacks deliver curated supplement bundles for targeted health needs—so your routine feels simpler, more supported, and more cost-effective.
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=Metagenics practitioner-designed supplement stack featuring Clear Change® 10-Day Detox, UltraFlora® Triplebiotic, Vitamin D3 10,000 IU, and OmegaGenics® Fish Oil. Labeled lab tested, clinically studied, and pure formula.
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Meet the Experts Behind the Stacks

Clinically Trusted. Personally Recommended.
Featured Products
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Browse PracStacks by Health Goal

Find the Supplement Stack That Fits Your Needs
Product List
  • PracStack
    Metagenics Gut Relief Duo for IBS-D PracStack showing UltraFlora Acute Care Probiotic and SpectraZyme Pancreatic Enzymes bottles, curated by Dr. Jen Stagg, ND, to support digestive balance, reduce constipation, and restore gut comfort.
    Gut Relief Duo for Occasional Bowel Distress
    Curated by Dr. Jen Stagg, ND
    $73.65
    $105.20
    • checkmark Support digestive balance
    • checkmark Reduce constipation
    • checkmark Restore comfort
    Shop Now
  • PracStack
    Metagenics Precision Weight & Hormone Balance for Women PracStack showing Wellness Essentials Women’s Daily Packs with Berberine GT and UltraFlora Women’s Complete Probiotic bottles, curated by Dr. Bridget Briggs, MD, to support metabolism, blood sugar balance, and healthy weight management.
    Precision Weight & Hormone Balance for Women
    Curated by Dr. Bridget Briggs, MD
    $138.54
    $197.90
    • checkmark Enhance metabolism
    • checkmark Stabilize blood sugar
    • checkmark Support fat loss naturally
    Shop Now
  • PracStack
    Metagenics Total Body Reset for Renewed Vitality PracStack showing Clear Change 10-Day Detox Program box with complementary Metagenics supplement bottles, curated by Dr. Patricia Guevara, MD, to support gentle detoxification, cellular renewal, and daily energy balance.
    Total Body Reset for Renewed Vitality
    Curated by Dr. Patricia Guevara, MD
    $195.73
    $279.60
    • checkmark Promote gentle detoxification
    • checkmark Cellular renewal
    • checkmark Daily energy balance
    Shop Now
  • PracStack
    Metagenics Calm Mood & Stress Resilience for Women PracStack showing SeroSyn Stress capsules alongside complementary supplement bottles, curated by Dr. Melissa Blake, ND, to support mood balance, focus, and healthy stress response for women.
    Calm Mood & Stress Resilience for Women
    Curated by Dr. Blake, ND
    $124.37
    $177.65
    • checkmark For women 40+
    • checkmark Balances mood and improves focus
    • checkmark Supports healthy cortisol levels
    Shop Now
Testimonials

Over 1,000 5-Star Product Reviews

See how our products transform real lives.
  • Metagenics Gut Relief Duo for IBS-D supplement stack icon showing UltraFlora Acute Care Probiotic and SpectraZyme Pancreatic Enzymes bottles, representing practitioner-curated digestive support for gut balance and comfort.

    Leslie D.

    gold stars ✓ Verified Customer, UltraFlora® Acute Care Probiotic “I have this product sent every month so I don't miss a dose. It keeps me feeling great and my digestive system working as it should.” Shop Gut Relief Stack
  • Metagenics Precision Weight & Hormone Balance for Women supplement stack icon showing Wellness Essentials Women’s Daily Packs with Berberine GT and UltraFlora Women’s Complete Probiotic bottles, representing practitioner-curated metabolic and hormone support.

    Deb M.

    gold stars ✓ Verified Customer, Berberine GT, Blood Sugar Supplement “Berberine works great to metabolize sugars and bring balance. I've used it for years and will continue... My doctor monitors all of my levels closely and is pleased with the effect.” Shop Weight & Hormone Stack
  • Metagenics Calm Mood & Stress Resilience for Women supplement stack icon featuring SeroSyn Stress capsules with OmegaGenics EPA-DHA and UltraFlora Women’s Complete Probiotic bottles, representing practitioner-curated mood and stress support.

    Whitney J.

    gold stars ✓ Verified Customer, SeroSyn™, Stress Supplement “My doctor recommended this in lieu of an antidepressant, and it absolutely helps my stress, depression, and mood fluctuations. High quality and effective! Delivery is also super quick!” Shop Calm Mood Stack
Clinical Insight

Supplement Stacks Backed by Clinical Insight.

  • Healthcare practitioner icon representing licensed Metagenics professionals who curate personalized supplement stacks.

    Practitioner-Curated

    Each supplement stack is built by a licensed Metagenics healthcare professional with years of clinical experience.
  • Group and medical plus icon representing real-world clinical results from practitioner-recommended Metagenics supplement bundles used in medical practice.

    Real-World Results

    These supplement bundles are used in medical practice to support real health outcomes and transform patient lives.
  • Capsule and tablet icon representing targeted Metagenics supplement support for specific health needs such as sleep, stress, or digestion.

    Targeted Support

    Each supplement stack addresses a specific health need—like sleep, stress, or digestion—with formulas that work better together.
HerWellness Hero Banner - Optimized
Portrait of Dr. Melissa Blake, Metagenics practitioner since 2013, standing in a bright office with plants and shelving, used alongside a quote about mood support, inflammation, nutrient status, and the gut-brain connection.l
“Mood is shaped by inflammation, nutrient status, and the gut-brain connection. When those systems are supported, it’s easier to feel grounded, clear, and resilient.”
Dr. Melissa Blake Metagenics practitioner since 2013
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Backed by Real Research. Designed for Real Life.

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We don’t just say it works. We prove it.

From ingredient sourcing to finished product, all Metagenics supplements are NSF-certified and third-party tested to ensure purity, potency, and safety of every formula.
Learn more
Laboratory scientist wearing protective eyewear and gloves conducts supplement quality testing with glass beakers and lab instruments, representing Metagenics’ commitment to research-driven formulation, safety, and product efficacy.
*Disclaimer: The information provided is for general educational purposes only and is not intended as medical advice. Individual needs may vary, and we recommend consulting your healthcare provider before making any changes to your health regimen.