skip to content
Home
Cart
Welcome!

New Customer?Create Account

UltraInflamX Plus 360°®

Support compromised gut function from inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s.* With 26 g of plant-based protein (daily dose).

Liver & Detox
Digestion & Probiotics
Immune Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Select Flavor

Why you’ll love UltraInflamX Plus 360°®

IBD puts your body in a difficult position: chronic intestinal inflammation increases your need for specific nutrients while making it harder to absorb them. Standard supplements aren't built for that.

UltraInflamX Plus 360°® is a medical food formulated specifically for patients with IBD, including ulcerative colitis and Crohn's disease, to address both the nutritional gaps and the intestinal signaling processes that come with active inflammation.*

UltraInflamX Plus 360°® provides targeted nutrition for:

  • Digestive inflammation*
  • Food sensitivities*
  • Compromised gut function from IBD*

It also supports your body during digestive flare-ups*:

  • Restores healthy digestion*
  • Strengthens your gut barrier*
  • Replenishes depleted nutrients*
  • Helps restore gut balance*

The Science Inside

Every component of this formula is selected to address a specific nutritional or physiological challenge associated with IBD.

  • Clinically studied curcumin that actually absorbs. CurQfen delivers up to 45.5x more free curcuminoids in human plasma than standard curcumin extract, so you're getting the full benefit of one of the most researched botanicals in gut health.*
  • Targeted intestinal signaling support. Xanthohumol, a next-generation SKRM from hops, may beneficially influence kinases and signaling molecules that impact intestinal comfort and function.*
  • Gut lining repair. L-glutamine is a primary energy source for the cells lining your intestinal wall, supporting tight junction integrity and mucosal repair.*
  • Microbiome support built in. Prebiotic IMOs encourage SCFA production to promote a healthy intestinal environment and increase beneficial bacteria.*
  • 26 g plant-based protein per serving. Complete protein support for patients whose absorption is compromised.*
  • 20+ essential vitamins and minerals. Methylated B12, bioavailable folate, zinc, magnesium, vitamin D, and selenium, targeting the nutrient deficiencies most common in IBD.

Triple tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Triple tested: All our products are verified for identity, purity, strength, and stability at three levels of production: ingredient, formula, and encapsulation.
  • Metagenics is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Gluten-free | Sugar-free | Dairy-free | Soy-free | No fillers | No preservatives | Vegetarian | No artificial colors | Plant-based

<tr

IngredientsAmount Per Serving
Serving Size2 Scoops (46 g)
Servings per Container14
Calories170
Total Fat7 g
Saturated Fat†1.5 g
Trans Fat0 g
Polyunsaturated Fat1.5 g
Monounsaturated Fat2.5 g
Cholesterol0 mg
Sodium120 mg
Total Carbohydrate14 g
Dietary Fiber2 g
Total Sugars2 g
Includes 1g Added Sugars
Protein13 g††
Typical Amino Acid Profile per Serving§
Amino Acidmg/Serving
L-Alanine590 mg
L-Arginine***1,080 mg
L-Aspartic Acid1,580 mg
L-Cystine (Cysteine)***140 mg
L-Glutamic Acid2,470 mg
L-Glutamine***750 mg
Glycine***540 mg
L-Histidine**320 mg
L-Isoleucine (BCAA)**1,020 mg
L-Leucine (BCAA)**1,870 mg
L-Lysine**1,700 mg
L-Methionine**160 mg
L-Phenylalanine**720 mg
L-Proline***620 mg
L-Serine***710 mg
L-Threonine**520 mg
L-Tryptophan**130 mg

Other Ingredients: Pea protein isolate, isomalto-oligosaccharide, organic cocoa powder (processed with alkali),^ rice protein concentrate, rice bran, calcium citrate, olive oil, flaxseed powder, magnesium citrate, natural flavors,^^ medium-chain triglycerides, L-lysine HCl, silica, L-leucine, L-glutamine, L-valine, dipotassium phosphate, L-isoleucine, rice protein matrix and polyphenols from hops extract, proprietary mix of curcumin and fenugreek galactomannans, quercetin, vitamin and mineral blend (zinc gluconate, ascorbic acid, manganese gluconate, d-alpha tocopheryl acetate, copper gluconate, D-biotin, retinyl palmitate, niacinamide, cholecalciferol, calcium D-pantothenate, chromium picolinate, pyridoxine HCl, riboflavin, potassium iodide, thiamin HCl, methylcobalamin, calcium L-5-methyltetrahydrofolate, and selenomethionine), malic acid, xanthan gum, ginger rhizome extract, rosemary leaf extract, Luo Han Guo fruit (monk fruit) extract, and guar gum.



SKU: UX2360C14

Dosage: Blend, shake, or briskly stir 2 scoops into 8 oz of chilled water or juice twice daily, or as directed by your healthcare practitioner. Who it’s for: UltraInflamX® Plus 360 is a medical food intended for the dietary management of IBD, including ulcerative colitis and Crohn’s disease. It is designed for use under the supervision of a healthcare practitioner and is not intended as a sole source of nutrition. It is appropriate for patients experiencing intestinal inflammation, compromised gut function, and potential malabsorption associated with IBD.*

Dry Place

  • NOTICE: THIS PRODUCT IS TO BE USED UNDER THE DIRECT SUPERVISION OF A PHYSICIAN OR OTHER LICENSED HEALTHCARE PRACTITIONER. DO NOT ENGAGE IN ANY DIET SUPPLYING LESS THAN 800 CALORIES PER DAY WITHOUT MEDICAL SUPERVISION.

Frequently bought together

  • UltraGI Replenish®

    Support for the management of compromised gut function with digestive disorders including malabsorption

    4.6

    Medical Food

    UltraGI Replenish®
  • UltraFlora® Balance Probiotic

    Daily probiotic for gut balance, digestive comfort, and immune support

    4.7

    Best Seller

    UltraFlora® Balance Probiotic
  • Vitamin D3 5000 + K

    Supports strong bones, heart, and immune health

    4.6

    Best Seller

    Vitamin D3 5000 + K
"I have had stomach issues in the past and when I was put on the UltraInflamX my problems cleared up in a matter of days."
Anna
The Science That Creates Balance®
Metagenics Special Ingredient Image
Metagenics delivers precision-crafted formulas to support your health—because true wellness starts with integrity, balance, & expertise.
Liver & Detox
Digestion & Probiotics
Immune Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Select Flavor

Why you’ll love UltraInflamX Plus 360°®

IBD puts your body in a difficult position: chronic intestinal inflammation increases your need for specific nutrients while making it harder to absorb them. Standard supplements aren't built for that.

UltraInflamX Plus 360°® is a medical food formulated specifically for patients with IBD, including ulcerative colitis and Crohn's disease, to address both the nutritional gaps and the intestinal signaling processes that come with active inflammation.*

UltraInflamX Plus 360°® provides targeted nutrition for:

  • Digestive inflammation*
  • Food sensitivities*
  • Compromised gut function from IBD*

It also supports your body during digestive flare-ups*:

  • Restores healthy digestion*
  • Strengthens your gut barrier*
  • Replenishes depleted nutrients*
  • Helps restore gut balance*

The Science Inside

Every component of this formula is selected to address a specific nutritional or physiological challenge associated with IBD.

  • Clinically studied curcumin that actually absorbs. CurQfen delivers up to 45.5x more free curcuminoids in human plasma than standard curcumin extract, so you're getting the full benefit of one of the most researched botanicals in gut health.*
  • Targeted intestinal signaling support. Xanthohumol, a next-generation SKRM from hops, may beneficially influence kinases and signaling molecules that impact intestinal comfort and function.*
  • Gut lining repair. L-glutamine is a primary energy source for the cells lining your intestinal wall, supporting tight junction integrity and mucosal repair.*
  • Microbiome support built in. Prebiotic IMOs encourage SCFA production to promote a healthy intestinal environment and increase beneficial bacteria.*
  • 26 g plant-based protein per serving. Complete protein support for patients whose absorption is compromised.*
  • 20+ essential vitamins and minerals. Methylated B12, bioavailable folate, zinc, magnesium, vitamin D, and selenium, targeting the nutrient deficiencies most common in IBD.

Triple tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Triple tested: All our products are verified for identity, purity, strength, and stability at three levels of production: ingredient, formula, and encapsulation.
  • Metagenics is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Gluten-free | Sugar-free | Dairy-free | Soy-free | No fillers | No preservatives | Vegetarian | No artificial colors | Plant-based

<tr

IngredientsAmount Per Serving
Serving Size2 Scoops (46 g)
Servings per Container14
Calories170
Total Fat7 g
Saturated Fat†1.5 g
Trans Fat0 g
Polyunsaturated Fat1.5 g
Monounsaturated Fat2.5 g
Cholesterol0 mg
Sodium120 mg
Total Carbohydrate14 g
Dietary Fiber2 g
Total Sugars2 g
Includes 1g Added Sugars
Protein13 g††
Typical Amino Acid Profile per Serving§
Amino Acidmg/Serving
L-Alanine590 mg
L-Arginine***1,080 mg
L-Aspartic Acid1,580 mg
L-Cystine (Cysteine)***140 mg
L-Glutamic Acid2,470 mg
L-Glutamine***750 mg
Glycine***540 mg
L-Histidine**320 mg
L-Isoleucine (BCAA)**1,020 mg
L-Leucine (BCAA)**1,870 mg
L-Lysine**1,700 mg
L-Methionine**160 mg
L-Phenylalanine**720 mg
L-Proline***620 mg
L-Serine***710 mg
L-Threonine**520 mg
L-Tryptophan**130 mg

Other Ingredients: Pea protein isolate, isomalto-oligosaccharide, organic cocoa powder (processed with alkali),^ rice protein concentrate, rice bran, calcium citrate, olive oil, flaxseed powder, magnesium citrate, natural flavors,^^ medium-chain triglycerides, L-lysine HCl, silica, L-leucine, L-glutamine, L-valine, dipotassium phosphate, L-isoleucine, rice protein matrix and polyphenols from hops extract, proprietary mix of curcumin and fenugreek galactomannans, quercetin, vitamin and mineral blend (zinc gluconate, ascorbic acid, manganese gluconate, d-alpha tocopheryl acetate, copper gluconate, D-biotin, retinyl palmitate, niacinamide, cholecalciferol, calcium D-pantothenate, chromium picolinate, pyridoxine HCl, riboflavin, potassium iodide, thiamin HCl, methylcobalamin, calcium L-5-methyltetrahydrofolate, and selenomethionine), malic acid, xanthan gum, ginger rhizome extract, rosemary leaf extract, Luo Han Guo fruit (monk fruit) extract, and guar gum.



SKU: UX2360C14

Dosage: Blend, shake, or briskly stir 2 scoops into 8 oz of chilled water or juice twice daily, or as directed by your healthcare practitioner. Who it’s for: UltraInflamX® Plus 360 is a medical food intended for the dietary management of IBD, including ulcerative colitis and Crohn’s disease. It is designed for use under the supervision of a healthcare practitioner and is not intended as a sole source of nutrition. It is appropriate for patients experiencing intestinal inflammation, compromised gut function, and potential malabsorption associated with IBD.*

Dry Place

  • NOTICE: THIS PRODUCT IS TO BE USED UNDER THE DIRECT SUPERVISION OF A PHYSICIAN OR OTHER LICENSED HEALTHCARE PRACTITIONER. DO NOT ENGAGE IN ANY DIET SUPPLYING LESS THAN 800 CALORIES PER DAY WITHOUT MEDICAL SUPERVISION.

Frequently bought together

Frequently Asked Questions

IBD creates specific nutritional challenges that general supplements are not designed to address. Patients with ulcerative colitis and Crohn’s disease often experience malabsorption, increased nutrient losses, and elevated demands for specific vitamins and minerals due to chronic intestinal inflammation.

The nutrients most commonly depleted in IBD include zinc, magnesium, vitamin D, iron, B12, and folate. Beyond micronutrients, IBD patients also benefit from targeted support for the gut lining, intestinal signaling pathways, and the microbiome.

UltraInflamX Plus 360°® is a medical food specifically formulated to address these needs in a single daily serving, under healthcare practitioner supervision.*

CurQfen is a patented curcumin-fenugreek complex developed to address one of the main limitations of standard curcumin: poor bioavailability. Standard curcumin extract is poorly absorbed in the gut, meaning most of what is consumed is never actually available for use by the body.

CurQfen uses fenugreek-derived dietary fiber to significantly enhance curcumin absorption. A randomized double-blind crossover study demonstrated that CurQfen delivers up to 45.5x more free curcuminoids in human plasma compared to standard curcumin extract.* Research suggests curcumin may influence inflammatory signaling pathways including NF-kB and Nrf2, and may help support the body’s antioxidant defenses.* UltraInflamX Plus 360°® provides 500mg of CurQfen per daily dose.*

Xanthohumol is a prenylated flavonoid found in hops (Humulus lupulus) and a Selective Kinase Response Modulator (SKRM). SKRMs work by influencing specific kinases and signaling molecules involved in the body’s inflammatory and oxidative stress responses, rather than broadly suppressing them.

Research suggests xanthohumol may beneficially influence kinases and signaling molecules that affect intestinal comfort and function,* and demonstrates potent antioxidant activity through Nrf2 signaling pathways.*

UltraInflamX Plus 360°® delivers xanthohumol via XNT ProMatrix, a proprietary protein matrix technology designed for enhanced bioavailability and stability.*

UltraInflamX Plus 360°® is a medical food formulated to meet the specialized nutritional needs of patients with IBD, and may be used with patients who have ulcerative colitis.* It is designed for use under the supervision of a healthcare practitioner as part of a targeted nutritional management plan.

The formula addresses multiple aspects of IBD nutrition simultaneously: intestinal signaling support via CurQfen and xanthohumol, mucosal repair support via L-glutamine, prebiotic fiber via IMOs, and 20+ essential vitamins and minerals to address common nutrient gaps in IBD patients.* As with any medical food, it should be used alongside, not as a replacement for, your healthcare practitioner’s recommended treatment plan.

UltraInflamX Plus 360°® is formulated to meet the specialized nutritional needs of patients with IBD, and may be used with patients who have Crohn’s disease.* Crohn’s disease is associated with significant nutritional challenges including protein-energy malnutrition, micronutrient deficiencies, and impaired absorption across multiple sections of the gastrointestinal tract.

This formula addresses those challenges with 26g of plant-based protein, bioavailable forms of B12 and folate, zinc, vitamin D, and magnesium, alongside targeted gut support from CurQfen, xanthohumol, L-glutamine, and prebiotic IMOs.* Use under healthcare practitioner supervision as part of a broader Crohn’s disease management plan.

Both are Metagenics medical food powders designed for patients with compromised gut function, but they address different clinical situations.

UltraGI Replenish® is formulated for general compromised gut function with digestive disorders and malabsorption. It features PreBiome 2’FL (HMO prebiotic), L-Alanyl-L-Glutamine for mucosal repair, and a comprehensive micronutrient profile to address nutrient gaps from malabsorption.*

UltraInflamX Plus 360°® is formulated specifically for IBD, including ulcerative colitis and Crohn’s disease. It adds CurQfen curcumin and xanthohumol to address the intestinal inflammatory signaling processes that are central to IBD, along with a higher protein dose (26g) and a broader phytonutrient complex from rosemary, ginger, and turmeric.*

Speak with your healthcare practitioner to determine which formula is appropriate for your specific needs.

Yes. UltraInflamX Plus 360°® is gluten-free, allergen-free, and non-GMO. The protein base is vegan, derived from pea and rice sources, with no dairy, soy, egg, or fish-derived ingredients. It contains no fillers and no preservatives.

As with any medical food, consult your healthcare practitioner before use, particularly if you are managing a complex health condition or have a history of severe allergies. Your practitioner can confirm that UltraInflamX Plus 360°® fits your individual nutritional management plan.

Customer Ratings & Reviews

Write A Review

Products you may like