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Vitamin B-Complex

Complex B vitamin supplement featuring active methylfolate & B12.*

Vitamins & Minerals
Essential Wellness
Stress, Mental Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Why you’ll love Vitamin B-Complex

Traditional B-complex supplements use synthetic forms that your body has to convert before using—an extra step that can affect how much is available for your body to absorb.

Vitamin B-Complex features nature-identical L-methylfolate & methylcobalamin B12, plus 10 other high-potency B vitamins and complementary nutrients, to support energy production, a balanced stress response, and healthy homocysteine levels.


Triple tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Triple tested: All our products are verified for identity, purity, strength, and stability at three levels of production: ingredient, formula, and encapsulation.
  • Metagenics is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Vegetarian

IngredientsAmount Per Serving% Daily Value
Serving Size1 Tablet
Servings Per Container60
Vitamin C (as ascorbic acid)125 mg139%
Thiamin (as thiamin mononitrate)14 mg1,167%
Riboflavin16 mg1,231%
Niacin (as niacinamide and niacin)200 mg1,250%
Vitamin B6 (as pyridoxine HCl)22 mg1,294%
Folate (as calcium L-5-methyltetrahydrofolate)†665 mcg DFE166%
Vitamin B12 (as methylcobalamin)250 mcg10,417%
Biotin250 mcg833%
Pantothenic Acid (as D-calcium pantothenate)75 mg1,500%
Choline (as choline bitartrate)100 mg18%
Myo-Inositol94 mg**
para-Aminobenzoic Acid (PABA)15 mg**
**Daily Value not established.

Other Ingredients: Microcrystalline cellulose, stearic acid (vegetable), silica, magnesium stearate (vegetable), and coating (hypromellose, medium-chain triglycerides, and hydroxypropylcellulose).



SKU: GL022

Take one tablet twice daily or as directed by your healthcare practitioner.

Dry Place

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A hand holds a yellow vitamin pill. Text explains that stress, poor diet, and aging can deplete essential B vitamins needed for energy, focus, and vitality. A small citation reference appears below.
A close‑up of a single yellow pill on a white background. Text states that not all B vitamins are easy to absorb and that this B‑Complex uses more bioavailable forms.
A bottle of Metagenics Vitamin B‑Complex sits on a white surface. Next to it is a customer testimonial describing clearer thinking, better focus, steady energy, and improved stress resilience, attributed to a verified customer named Victoria.
A person looks upward and smiles with soft lighting behind them. Text highlights benefits such as natural all‑day energy, brain and nervous system support, and improved resilience to daily stress.
Vitamins & Minerals
Essential Wellness
Stress, Mental Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Why you’ll love Vitamin B-Complex

Traditional B-complex supplements use synthetic forms that your body has to convert before using—an extra step that can affect how much is available for your body to absorb.

Vitamin B-Complex features nature-identical L-methylfolate & methylcobalamin B12, plus 10 other high-potency B vitamins and complementary nutrients, to support energy production, a balanced stress response, and healthy homocysteine levels.


Triple tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Triple tested: All our products are verified for identity, purity, strength, and stability at three levels of production: ingredient, formula, and encapsulation.
  • Metagenics is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Vegetarian

IngredientsAmount Per Serving% Daily Value
Serving Size1 Tablet
Servings Per Container60
Vitamin C (as ascorbic acid)125 mg139%
Thiamin (as thiamin mononitrate)14 mg1,167%
Riboflavin16 mg1,231%
Niacin (as niacinamide and niacin)200 mg1,250%
Vitamin B6 (as pyridoxine HCl)22 mg1,294%
Folate (as calcium L-5-methyltetrahydrofolate)†665 mcg DFE166%
Vitamin B12 (as methylcobalamin)250 mcg10,417%
Biotin250 mcg833%
Pantothenic Acid (as D-calcium pantothenate)75 mg1,500%
Choline (as choline bitartrate)100 mg18%
Myo-Inositol94 mg**
para-Aminobenzoic Acid (PABA)15 mg**
**Daily Value not established.

Other Ingredients: Microcrystalline cellulose, stearic acid (vegetable), silica, magnesium stearate (vegetable), and coating (hypromellose, medium-chain triglycerides, and hydroxypropylcellulose).



SKU: GL022

Take one tablet twice daily or as directed by your healthcare practitioner.

Dry Place

Frequently bought together

Frequently Asked Questions

B12 is one of eight essential B vitamins, and is a common source of deficiency. B12 plays a critical role in energy production and nervous system health, but it’s just one in a whole family of eight B vitamins.

A B-complex supplement provides all eight, supporting energy production, stress response, and homocysteine levels together. Some B-complex supplements feature nature-identical, activated forms, which are more readily available for your body to use.

L-methylfolate is the nature-identical, active form of folate (vitamin B9)—meaning it's ready for your body to use without conversion. Most conventional supplements use folic acid, which the body has to convert before it can be used. This step can be a barrier for those with genetic variations that affect folate conversion, such as MTHFR.

Vitamin B-Complex features L-methylfolate alongside methylcobalamin B12. Other supplements, like Intrinsi B12-Folate™, also feature both nutrients in activated forms with added intrinsic factor for enhanced absorption.

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